BMP3 蛋白
Quick Overview for BMP3 蛋白 (ABIN2468285)
抗原
See all BMP3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MQWIEPRNCA RRYLKVDFAD IGWSEWIISP KSFDAYYCSG ACQFPMPKSL KPSNHATIQS IVRAVGVVPG IPEPCCVPEK MSSLSILFFD ENKNVVLKVY PNMTVESCAC R
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产品特性
- Biological activity was determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Bone Morphogenetic Protein 3 (BMP3) (AA 373-472) protein (GST tag)
BMP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 3 (BMP3) (AA 1-472) protein (GST tag)BMP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 3 (BMP3) (AA 363-472) protein (His tag)BMP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Bone Morphogenetic Protein 3 (BMP3) protein (Myc-DYKDDDDK Tag)BMP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing BMP-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- BMP3 (Bone Morphogenetic Protein 3 (BMP3))
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别名
- BMP-3
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背景
- TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone, and to a lesser extent fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant human BMP-3 is a disulfide linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein.
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基因ID
- 651
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NCBI登录号
- NP_001192
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OMIM
- 126507087
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UniProt
- P12645
抗原
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