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Defensin beta 3 Protein (DEFB3)

This Recombinant Defensin beta 3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2468266
发货至: 中国
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Quick Overview for Defensin beta 3 Protein (DEFB3) (ABIN2468266)

抗原

See all Defensin beta 3 (DEFB3) 蛋白
Defensin beta 3 (DEFB3)

蛋白类型

Recombinant

宿主

  • 3
  • 3
  • 1
  • 1

资源

  • 4
  • 2
大肠杆菌(E. Coli)

纯度

< 98 % by SDS-PAGE gel and HPLC analyses.
  • 序列

    GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing BD3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BD3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    Defensin beta 3 (DEFB3)

    别名

    BD-3

    背景

    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified , BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Recombinant Human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.

    基因ID

    55894

    NCBI登录号

    NP_061131

    OMIM

    8923890

    UniProt

    P81534

    途径

    Production of Molecular Mediator of Immune Response
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