ADIPOQ 蛋白
Quick Overview for ADIPOQ 蛋白 (ABIN2468217)
抗原
See all ADIPOQ 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- RGHHHHHHHH VTTTEELAPA LVPPPKGTCA GWMAGIPGHP GHNGTPGRDG RDGTPGEKGE KGDAGLLGPK GETGDVGMTG AEGPRGFPGT PGRKGEPGEA AYVYRSAFSV GLETRVTVPN VPIRFTKIFY NQQNHYDGST GKFYCNIPGL YYFSYHITVY MKDVKVSLFK KDKAVLFTYD QYQEKNVDQA SGSVLLHLEV GDQVWLQVYG DGDHNGLYAD NVNDSTFTGF LLYHDTN
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产品特性
- Determined by a cytotoxic assay using M1 cells. The ED50 for this effect is 4.0-6.0 μg/mL.
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Adiponectin (ADIPOQ) (Active) protein
ADIPOQ 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Adiponectin (ADIPOQ) (AA 19-244) protein (His tag)ADIPOQ 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 19-244) protein (Fc Tag)ADIPOQ 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (Fc Tag)ADIPOQ 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Adiponectin (ADIPOQ) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Adiponectin (ADIPOQ) (AA 111-247) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Adiponectin (ADIPOQ) (AA 111-210) protein (GST tag)ADIPOQ 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Adiponectin (ADIPOQ) (AA 111-247) proteinADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Adiponectin (ADIPOQ) proteinADIPOQ 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing Adiponectin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Adiponectin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- Adiponectin
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背景
- Adiponectin is an adipose-derived secreted protein containing 236 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01 % of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-beta and class A scavenger receptor in macrophages). Recombinant adiponectin is a multimeric glycoprotein containing amino acids Val-18 to Asn-247 of the adiponectin precursor protein fused to an N-terminal histidine tag. Monomeric glycosylated adiponectin migrates at an apparent molecular weight of approximately 25.9 kDa by SDS PAGE analysis under reducing conditions.
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基因ID
- 11450
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NCBI登录号
- NP_033735
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OMIM
- 87252711
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UniProt
- Q60994
抗原
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