VEGF Protein (AA 27-191)
(3 references)-
- 抗原 See all VEGF 蛋白
- VEGF (Vascular Endothelial Growth Factor (VEGF))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-191
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宿主
- 人
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资源
- HEK-293 Cells
- 品牌
- ActiveMax®
- 序列
- AA 27-191
- 产品特性
- This protein carries no "tag". The protein has a calculated MW of 19 kDa (monomer). As a result of glycosylation, the protein migrates as 24 kDa (monomer) under reducing (R) condition, and 43-50 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE).
- 纯度
- >98 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- 质量等级
- HPLC verified
- Top Product
- Discover our top product VEGF 蛋白
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Vascular Endothelial Growth Factor (VEGF) (AA 27-191) (Active) protein (Biotin)
VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (Active) proteinVEGF 宿主: 人 宿主: Yeast (Pichia pastoris) > 95 % by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-191) (Active) protein (His tag)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-147) (Active) protein (AVI tag,His tag,Biotin)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (Active) proteinVEGF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-147) (Active) protein (His tag)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "Creation of different bioluminescence resonance energy transfer based biosensors with high affinity to VEGF." in: PLoS ONE, Vol. 15, Issue 3, pp. e0230344, (2020) (PubMed).
: "FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK." in: Cellular and molecular life sciences : CMLS, (2020) (PubMed).
: "A biosynthetic route for polysialylating proteins in Escherichia coli." in: Metabolic engineering, Vol. 44, pp. 293-301, (2018) (PubMed).
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: "Creation of different bioluminescence resonance energy transfer based biosensors with high affinity to VEGF." in: PLoS ONE, Vol. 15, Issue 3, pp. e0230344, (2020) (PubMed).
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- 抗原
- VEGF (Vascular Endothelial Growth Factor (VEGF))
- 别名
- VEGF (VEGF 产品)
- 背景
- VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.
- 分子量
- 19.2 kDa
- NCBI登录号
- NP_001165097
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