G-CSF Protein (AA 31-204)
Our Local Distributor
北京 101111
Quick Overview for G-CSF Protein (AA 31-204) (ABIN2181135)
抗原
See all G-CSF (CSF3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
产品特性
- AA 31-204
-
品牌
- ActiveMax®
-
序列
- AA 31-204
-
产品特性
- This protein carries no "tag". The protein has a calculated MW of 18.7 kDa. The protein migrates as 18-21 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
-
过滤
- 0.22 μm filtered
-
内毒素水平
- Less than 1.0 EU per μg by the LAL method.
-
-
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (Active) protein
CSF3 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (Active) proteinCSF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (AA 31-208) (Active) proteinCSF3 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 3 (Granulocyte) (CSF3) protein (His tag)CSF3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (AA 22-214) protein (His-IF2DI Tag)CSF3 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (AA 1-207) protein (GST tag)CSF3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Colony Stimulating Factor 3 (Granulocyte) (CSF3) (AA 31-204) (Active) proteinCSF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, AcA Active
Colony Stimulating Factor 3 (Granulocyte) (CSF3) proteinCSF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS
Colony Stimulating Factor 3 (Granulocyte) (CSF3) proteinCSF3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Colony Stimulating Factor 3 (Granulocyte) (CSF3) proteinCSF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- PBS, pH 7.4
-
注意事项
- Please avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
-
-
- G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
-
别名
- G-CSF
-
背景
- Granulocyte colony-stimulating factor (G-CSF or GCSF) is also known as colony-stimulating factor 3, CSF3, C17orf33, CSF3OS, GCSF, MGC45931. It is a glycoprotein, growth factor and cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to release them into the blood. G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. G-CSF regulates them using Janus kinase (JAK)/signal transducer and activator of transcription (STAT) and Ras /mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signal transduction pathway. G-CSF is produced by endothelium, macrophages, and a number of other immune cells. The natural human glycoprotein exists in two forms, a 174- and 180-amino-acid-long protein of molecular weight 19,600 grams per mole. G-CSF can effect on the hematopoietic system and neuronal cells as a neurotrophic factor. The action of G-CSF in the central nervous system is to induce neurogenesis, to increase the neuroplasticity and to counteract apoptosis. G-CSF stimulates the production of white blood cells (WBC). In oncology and hematology, a recombinant form of G-CSF is used with certain cancer patients to accelerate recovery from neutropenia after chemotherapy, allowing higher-intensity treatment regimens. Another form of recombinant human G-CSF called lenograstim is synthesised in Chinese Hamster Ovary cells (CHO cells). The recombinant human G-CSF synthesised in an E. coli expression system is called filgrastim.
-
分子量
- 18.7 kDa
-
NCBI登录号
- NP_757373
-
途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
抗原
-
