BMP2 Protein (AA 284-396)
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Quick Overview for BMP2 Protein (AA 284-396) (ABIN2180654)
抗原
See all BMP2 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 284-396
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序列
- AA 284-396
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产品特性
- This protein carries no "tag". The protein has a calculated MW of 13 kDa. the protein migrates as 13 kDa under reducing (R) condition, and 24 kDa under non-reducing (NR) condition (SDS-PAGE).
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 100 mM Acetic Acid, pH 2.8
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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别名
- BMP-2
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背景
- Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.
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分子量
- 12.8 kDa
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NCBI登录号
- NP_001191
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
抗原
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