Thyroperoxidase Protein (full length)
Quick Overview for Thyroperoxidase Protein (full length) (ABIN2132174)
抗原
See all Thyroperoxidase (TPO) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- full length
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产品特性
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Purified recombinant Human Thyroid Peroxidase protein
Expression System: Sf-9 insect cells -
纯化方法
- Proprietary chromatographic technique
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Thyroid Peroxidase (TPO) (AA 19-846) protein (His tag)
TPO 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thyroid Peroxidase (TPO) (AA 32-834) protein (His tag)TPO 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thyroid Peroxidase (TPO) (AA 672-779) protein (GST tag)TPO 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Thyroid Peroxidase (TPO) (AA 1-933) protein (GST tag)TPO 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- Thyroid Peroxidase
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背景
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Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
Alternative Names: TPX protein, MSA protein, TPO protein -
分子量
- 101 kDa
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途径
- Thyroid Hormone Synthesis
抗原
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