IL-4_CD88 (AA 25-153) protein (His tag)
This Recombinant IL-4_CD88 protein is expressed in 人细胞.
产品编号 ABIN2115442
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for IL-4_CD88 (AA 25-153) protein (His tag) (ABIN2115442)
抗原
IL-4_CD88
蛋白类型
Recombinant
宿主
人
资源
人细胞
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 25-153
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标记
- His tag
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原理
- Recombinant Human Interleukin-4/IL-4 (C-6His)
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序列
- HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSSV DHHHHHH
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产品特性
- Recombinant Human Interleukin-4/IL-4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (His25-Ser153) of Human IL-4 fused with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- IL-4_CD88
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背景
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Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
Synonyms: Interleukin-4, IL-4, B-Cell Stimulatory Factor 1, BSF-1, Binetrakin, Lymphocyte Stimulatory Factor 1, Pitrakinra, IL4 -
分子量
- 16 kDa
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UniProt
- P05112
抗原
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