Thrombopoietin Protein (THPO) (AA 22-356)
Quick Overview for Thrombopoietin Protein (THPO) (AA 22-356) (ABIN2018397)
抗原
See all Thrombopoietin (THPO) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 22-356
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产品特性
- ED50 < 2 ng /mL, measured in a proliferation assay using MO7e cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Thrombopoietin (THPO) protein (His tag)
THPO 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Thrombopoietin (THPO) (AA 23-195) protein (His tag)THPO 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) (AA 22-195) protein (His-IF2DI Tag)THPO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) (AA 1-349) protein (GST tag)THPO 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Thrombopoietin (THPO) proteinTHPO 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Thrombopoietin (THPO) proteinTHPO 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL..
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant murine Thrombopoietin (TPO) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, murine Thrombopoietin (TPO) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- Thrombopoietin (THPO)
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别名
- Thrombopoietin (TPO)
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背景
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Thrombopoietin (TPO), also known as C-mpl ligand, MGDF and Thpo, is a glycoprotein hormone belonging to the EPO/TPO family. It is expressed mainly in the liver, kidney and skeletal muscle. TPO binds and signals through MLP/C_MPL receptor. It stimulates the proliferation and maturation of megakaryocytes from their committed progenitor cells, and it regulates the production and circulation of platelets. TPO has also been reported to promote the apoptosis of hypoxia-sensitized neurons and to inhibit neuronal differentiation.
Synonyms: Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF -
分子量
- 30-80 kDa, observed by reducing SDS-PAGE.
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UniProt
- P40226
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途径
- JAK/STAT Signaling, Hormone Activity
抗原
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