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SDF1 beta 蛋白

SDF1b 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN2018351
发货至: 中国
  • 抗原 See all SDF1 beta (SDF1b) 蛋白
    SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 4
    • 4
    • 2
    • 2
    资源
    • 10
    大肠杆菌(E. Coli)
    序列
    KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
    产品特性
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20-80 ng/mL.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    过滤
    0.2 μm filtered
    内毒素水平
    < 1 EU/μg of rHuSDF-1μ/CXCL12μ as determined by LAL method.
    Top Product
    Discover our top product SDF1b 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
    缓冲液
    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • 抗原
    SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
    别名
    SDF-1 beta/cxcl12 (SDF1b 产品)
    别名
    Pbsf Protein, Scyb12 Protein, Sdf1 Protein, Tlsf Protein, Tpar1 Protein, sdf1a Protein, SDF-1 Protein, chemokine (C-X-C motif) ligand 12 Protein, C-X-C motif chemokine ligand 12 Protein, Cxcl12 Protein, cxcl12 Protein, CXCL12 Protein
    背景
    Stromal-Cell Derived Factor-1 beta (SDF-1 beta), also known as SCYB12, PBSF and CXCL12, is an 8.3 kDa, heparin-binding member of the CXC (or alpha) family of chemokines and signal through the CXCR4 receptor. SDF-1 alpha and beta are reported to be monomers at neutral pH and physiologic ionic strength, On the cell surface, this may well facilitate SDF-1 interaction with its two receptors, CXCR4 and syndecan4. Heparin sulfate is known to protect SDF-1 from proteolysis, and CXCR4 exists constitutively as a dimer. Among its many functions, CXCL12 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis (12, 13). It also enhances the survival of myeloid progenitor cells
    Synonyms: Human Stromal-Cell Derived Factor-1 beta, Human SDF-1 beta
    分子量
    8.5 kDa, a single non-glycosylated polypeptide chain containing 72 amino acid residues.
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