SDF1 beta 蛋白
Quick Overview for SDF1 beta 蛋白 (ABIN2018351)
抗原
See all SDF1 beta (SDF1b) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
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产品特性
- Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20-80 ng/mL.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1 EU/μg of rHuSDF-1μ/CXCL12μ as determined by LAL method.
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Stromal Cell Derived Factor 1 beta (SDF1b) (Active) protein
SDF1b 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Stromal Cell Derived Factor 1 beta (SDF1b) (Active) proteinSDF1b 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Stromal Cell Derived Factor 1 beta (SDF1b) (AA 22-93) protein (His tag)SDF1b 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
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缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
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别名
- SDF-1 beta/cxcl12
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背景
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Stromal-Cell Derived Factor-1 beta (SDF-1 beta), also known as SCYB12, PBSF and CXCL12, is an 8.3 kDa, heparin-binding member of the CXC (or alpha) family of chemokines and signal through the CXCR4 receptor. SDF-1 alpha and beta are reported to be monomers at neutral pH and physiologic ionic strength, On the cell surface, this may well facilitate SDF-1 interaction with its two receptors, CXCR4 and syndecan4. Heparin sulfate is known to protect SDF-1 from proteolysis, and CXCR4 exists constitutively as a dimer. Among its many functions, CXCL12 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis (12, 13). It also enhances the survival of myeloid progenitor cells
Synonyms: Human Stromal-Cell Derived Factor-1 beta, Human SDF-1 beta -
分子量
- 8.5 kDa, a single non-glycosylated polypeptide chain containing 72 amino acid residues.
抗原
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