PF4 Protein (AA 32-101)
Quick Overview for PF4 Protein (AA 32-101) (ABIN2018316)
抗原
See all PF4 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 32-101
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产品特性
- ED50 < 10 μg/mL, measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Platelet Factor 4 (PF4) (AA 32-101) protein (Fc Tag)
PF4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 30-105) protein (Fc Tag)PF4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag)PF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag,Biotin)PF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 1-101) protein (GST tag)PF4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Platelet Factor 4 (PF4) (AA 32-101) protein (His tag)PF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85% by SDS-PAGE SDS
Platelet Factor 4 (PF4) (AA 34-101) protein (Fc Tag)PF4 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant human platelet factor 4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human platelet factor 4 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- PF4 (Platelet Factor 4 (PF4))
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别名
- Platelet Factor 4/CXCL4
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背景
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Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the alpha-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Synonyms: PF-4, CXCL4, SCYB4,Platelet Factor-4, CXCL4, Oncostatin A, Ironplact -
分子量
- -7.8 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P02776
抗原
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