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NOG Protein (AA 28-232)

NOG 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018291
发货至: 中国
  • 抗原 See all NOG 蛋白
    NOG (Noggin (NOG))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 28-232
    宿主
    • 14
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    资源
    • 18
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    CHO Cells
    产品特性
    ED50<2.5 ng/mL, measured in a bioassay using ATDC5 cells in the presence of 10 ng/mL human BMP-4.
    纯度
    > 95 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product NOG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Noggin remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human Nogginshould be stable up to 1 week at 4°C or up to 2 months at -20°C.
    有效期
    6 months
  • 抗原
    NOG (Noggin (NOG))
    别名
    Noggin (NOG 产品)
    别名
    SYM1 Protein, SYNS1 Protein, nog-A Protein, nog1 Protein, noggin-1 Protein, noggin Protein, noggin Protein, noggin L homeolog Protein, noggin protein Protein, NOG Protein, Nog Protein, nog.L Protein, noggin Protein
    背景
    Noggin, also known as NOG, is a homodimeric glycoprotein that bindsto and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors. Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients, regulating cellular responses dependent on the local concentration of the signaling molecule.
    Synonyms: NOG
    分子量
    29-31kDa, observed by reducing SDS-PAGE.
    UniProt
    Q13253
    途径
    Stem Cell Maintenance, Tube Formation
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