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IL-2 Protein (AA 21-153)

This Recombinant IL-2 protein is expressed in CHO Cells.
产品编号 ABIN2018088
发货至: 中国
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Quick Overview for IL-2 Protein (AA 21-153) (ABIN2018088)

抗原

See all IL-2 (IL2) 蛋白
IL-2 (IL2) (Interleukin 2 (IL2))

蛋白类型

Recombinant

生物活性

Active

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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE.
  • 产品特性

    AA 21-153

    产品特性

    ED50 < 2 ng/mL, measured in a cell proliferation assay using CTLL-2 cells.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS..

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    Interleukin-2 (IL-2)

    背景

    Interleukin-2 (IL-2) is a Oglycosylated, four alpha-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, gamma delta T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
    Synonyms: T-cell growth factor (TCGF), Aldesleukin

    分子量

    15-16 kDa, observed by reducing SDS-PAGE.

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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