IL-19 Protein (AA 25-176)
-
- 抗原 See all IL-19 (IL19) 蛋白
- IL-19 (IL19) (Interleukin 19 (IL19))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-176
-
宿主
- 小鼠
-
资源
- 大肠杆菌(E. Coli)
- 产品特性
-
ED50 < 50 ng/mL, measured by a cell proliferation assay using MCF-7 cells, corresponding to a specific activity of > 2x 10^4 units/mg.
AA 25-176, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL19 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstituted in 50 mM acetic acid at 50 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 50 mM acetic acid.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant mouse Interleukin-19 (rmIL-19) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-19 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
-
- 抗原
- IL-19 (IL19) (Interleukin 19 (IL19))
- 别名
- Interleukin-19 (IL-19) (IL19 产品)
- 别名
- IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
- 背景
-
Interleukin-19 (IL-19) is a cytokine belonging to the interleukin family. Structurally, IL-19 is grouped into the IL-10 sub-family, which also includes IL-20, IL-22, IL-24, and IL-26. In contrast to IL-10, which exists as a homodimer, IL-19 is stable and active as a monomer in vivo. IL-19 functions through the receptor complex composed of IL-20 Receptor alpha and IL-20 Receptor beta, which is also utilized by IL-20 and IL-24. IL-19 is produced by active monocytes and stimulated synergistically by IL-17 and IL-13. The functions of IL-19 are to promote the development and function of Th2 cells and to enhance the production of Th2 cytokines. IL-19 is implicated in aging, vascular disease, Type I diabetes, and rheumatoid arthritis. Recombinant mouse Interleukin-19 (rmIL-19) produced in E. coli is a single non-glycosylated polypeptide chain containing of153 amino acids. A fully biologically active molecule, rmIL-19 has a molecular mass of 17.7 kDa analyzed by non-reducing SDS-PAGE.
Synonyms: Melanoma differentiation association like protein, MDA1, NG.1, ZMDA1, IL-10C, IL-19 - 分子量
- 17.7 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- Q8CJ70
-