IFNW1 蛋白
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- 抗原 See all IFNW1 (IFNW) 蛋白
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
- 产品特性
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/mL, corresponding to a specific activity of > 1.0 x 10^8 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 1 EU/μg of rHuIFN-μ as determined by LAL method.
- Top Product
- Discover our top product IFNW 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- 抗原
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- 别名
- Interferon omega (IFNW 产品)
- 别名
- IFNW1 Protein, interferon omega 1 Protein, interferon, omega 1 Protein, inteferon omega 1 Protein, IFNW1 Protein, LOC100155760 Protein, IFN-OMEGA1 Protein
- 背景
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Interferon-Omega (IFN-o) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a, IFN-b, and IFN-o. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-omega is derived from IFN-a/b and share 75 % sequence with IFN-a. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-a, IFN-b, and IFN-o that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells.
Synonyms: IFN Omega Human - 分子量
- 20.0 kDa, containing 172 amino acid residues with two conserved disulfide bonds.
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