IFNW1 蛋白
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北京 101111
Quick Overview for IFNW1 蛋白 (ABIN2017994)
抗原
See all IFNW1 (IFNW) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
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产品特性
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/mL, corresponding to a specific activity of > 1.0 x 10^8 IU/mg.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1 EU/μg of rHuIFN-μ as determined by LAL method.
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Interferon, omega 1 (IFNW) (AA 24-195) protein (His-IF2DI Tag)
IFNW 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Interferon, omega 1 (IFNW) (AA 1-195) protein (GST tag)IFNW 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Interferon, omega 1 (IFNW) protein (His tag)IFNW 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
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缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
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别名
- Interferon omega
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背景
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Interferon-Omega (IFN-o) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a, IFN-b, and IFN-o. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-omega is derived from IFN-a/b and share 75 % sequence with IFN-a. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-a, IFN-b, and IFN-o that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells.
Synonyms: IFN Omega Human -
分子量
- 20.0 kDa, containing 172 amino acid residues with two conserved disulfide bonds.
抗原
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