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GM-CSF Protein (AA 18-144)

CSF2 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2017905
发货至: 中国
  • 抗原 See all GM-CSF (CSF2) 蛋白
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 18-144
    宿主
    • 25
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    • 2
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    资源
    • 20
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    • 1
    CHO Cells
    产品特性
    ED50 < 0.2 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 5x10^6 units/mg.
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product CSF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    别名
    Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (CSF2 产品)
    别名
    GMCSF Protein, GM-CSF Protein, CSF2 Protein, Csfgm Protein, Gm-CSf Protein, MGI-IGM Protein, Gm-csf Protein, Gmcsf Protein, CSF Protein, colony stimulating factor 2 Protein, colony stimulating factor 2 (granulocyte-macrophage) Protein, CSF2 Protein, Csf2 Protein
    背景
    Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes,monocytes/macrophages and eosinophils. Human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can induce human endothelial cells to migrate and proliferate. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.
    Synonyms: Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
    分子量
    22-28 kDa, observed by non-reducing SDS-PAGE.
    途径
    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
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