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G-CSF Protein (AA 27-200)

This Recombinant G-CSF protein is expressed in CHO Cells.
产品编号 ABIN2017889
发货至: 中国

Quick Overview for G-CSF Protein (AA 27-200) (ABIN2017889)

抗原

See all G-CSF (CSF3) 蛋白
G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 27-200

    产品特性

    ED50< 0.1 ng/mL, determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells, corresponding to a specific activity of >1 x 10^7 units/mg.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant human Granulocyte Colony Stimulating Factor (G-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

    别名

    Granulocyte Colony Stimulating Factor (G-CSF)

    背景

    Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17.
    Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin.

    分子量

    18.7kDa, observed by non-reducing SDS-PAGE.

    UniProt

    Q8N4W3

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
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