G-CSF Protein (AA 27-200)
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Quick Overview for G-CSF Protein (AA 27-200) (ABIN2017889)
抗原
See all G-CSF (CSF3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 27-200
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产品特性
- ED50< 0.1 ng/mL, determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells, corresponding to a specific activity of >1 x 10^7 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant human Granulocyte Colony Stimulating Factor (G-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
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别名
- Granulocyte Colony Stimulating Factor (G-CSF)
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背景
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Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17.
Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin. -
分子量
- 18.7kDa, observed by non-reducing SDS-PAGE.
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UniProt
- Q8N4W3
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
抗原
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