GM-CSF Protein (AA 18-141)
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Quick Overview for GM-CSF Protein (AA 18-141) (ABIN2017886)
抗原
See all GM-CSF (CSF2) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 18-141
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产品特性
- ED50 < 0.05 ng/mL, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of >2 x 10^7 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant murine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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别名
- GM-CSF
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背景
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Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
Synonyms: Granulocyte/Macrophage-Colony Stimulating Factor, GMCSF -
分子量
- 15-19 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- Q14AD9
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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