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FGF18 Protein (AA 27-199)

This Recombinant FGF18 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2017817
发货至: 中国

Quick Overview for FGF18 Protein (AA 27-199) (ABIN2017817)

抗原

See all FGF18 蛋白
FGF18 (Fibroblast Growth Factor 18 (FGF18))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 6
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资源

  • 9
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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 产品特性

    AA 27-199

    产品特性

    ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
    AA 27 -199, expressed with an N-terminal Met.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    有效期

    6 months
  • 抗原

    FGF18 (Fibroblast Growth Factor 18 (FGF18))

    别名

    Fibroblast Growth Factor-18 (FGF-18)

    背景

    Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI

    分子量

    20.3 kDa, observed by reducing SDS-PAGE.

    UniProt

    O76093

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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