beta 2 Defensin 蛋白
This Recombinant beta 2 Defensin protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for beta 2 Defensin 蛋白 (ABIN2017676)
抗原
See all beta 2 Defensin (BD-2) 蛋白
beta 2 Defensin (BD-2)
(Defensin beta 2 (BD-2))
蛋白类型
Recombinant
生物活性
Active
宿主
小鼠
资源
大肠杆菌（E. Coli）
纯度
> 98 % by SDS-PAGE and HPLC analyses.
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序列
- AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
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产品特性
- Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration of 10-100 ng/mL.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1 EU/μg of rMuBD-2 as determined by LAL method.
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Defensin beta 2 (BD-2) (AA 21-71) protein (His-IF2DI Tag)
BD-2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
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缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))
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别名
- beta Defensin-2(BD-2)
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背景
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
Synonyms: BD 2 Murine , BD-2 Murine -
分子量
- 5.5 kDa, a single non-glycosylated polypeptide chain containing 51 amino acids.
抗原
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