ADIPOQ Protein (AA 21-247)
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Quick Overview for ADIPOQ Protein (AA 21-247) (ABIN2017655)
抗原
See all ADIPOQ 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 21-247
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产品特性
- ED50 < 5 μg/mL, measured by a cell growth inhibitory assay using M1 cells, corresponding to a specific activity of > 2x 10^2 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant mouse Adiponectin (rmAdiponectin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmAdiponectin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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有效期
- 6 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- Adiponectin
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背景
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Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. The receptors of Adiponectin are seven transmembrane G protein coupled receptors: Receptor 1 is expressed in skeletal muscle and Receptor 2 in liver. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes. Therefore, Adiponectin has promising potential as a pharmacological agent.Recombinant mouse Adiponectin (rmAdiponectin) produced in E. coli is a single non-glycosylated polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmAdiponectin has a molecular mass of 24.6 kDa analyzed by reducing SDS-PAGE.
Synonyms: Acrp-30, GBP-28, Apm-1 -
分子量
- 24.6 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q60994
抗原
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