MMP12 Protein (AA 106-267, Catalytic Domain)
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- 抗原 See all MMP12 蛋白
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- 蛋白类型
- Recombinant
- 产品特性
- AA 106-267, Catalytic Domain
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 产品特性
- The sequence corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. Coli.
- 纯化方法
- Purified from bacterial lysate and refolded using proprietary technique.
- Top Product
- Discover our top product MMP12 蛋白
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- 限制
- 仅限研究用
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- 储存条件
- -80 °C
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- 抗原
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- 别名
- MMP-12 (MMP12 产品)
- 别名
- MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein
- 背景
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54 kDa zymogen and becomes the mature 54 kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including alpha-1 proteinase inhibitor, alpha-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
- 分子量
- 18 kDa
- NCBI登录号
- NP_002417
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