MMP12 Protein (AA 106-267, Catalytic Domain)
This Recombinant MMP12 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for MMP12 Protein (AA 106-267, Catalytic Domain) (ABIN1883193)
抗原
See all MMP12 蛋白
MMP12
(Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
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产品特性
- AA 106-267, Catalytic Domain
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产品特性
- The sequence corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. Coli.
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纯化方法
- Purified from bacterial lysate and refolded using proprietary technique.
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Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) protein (His tag)
MMP12 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) protein (GST tag)MMP12 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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储存条件
- -80 °C
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- MMP-12
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背景
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54 kDa zymogen and becomes the mature 54 kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including alpha-1 proteinase inhibitor, alpha-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
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分子量
- 18 kDa
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NCBI登录号
- NP_002417
抗原
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