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IL-21 Protein (AA 23-155)

This Recombinant IL-21 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1880654
发货至: 中国
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Quick Overview for IL-21 Protein (AA 23-155) (ABIN1880654)

抗原

See all IL-21 (IL21) 蛋白
IL-21 (IL21) (Interleukin 21 (IL21))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 23-155

    原理

    Recombinant Human Interleukin-21/IL-21

    序列

    MQGQDRHMIR MRQLIDIVDQ LKNYVNDLVP EFLPAPEDVE TNCEWSAFSC FQKAQLKSAN TGNNERIINV SIKKLKRKPP STNAGRRQKH RLTCPSCDSY EKKPPKEFLE RFKSLLQKMI HQHLSSRTHG SEDS

    产品特性

    Recombinant Human Interleukin-21 is produced by our E.coli expression system and the target gene encoding Gln30-Ser162 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 um filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 weeks
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    Interleukin-21/IL-21

    Sub Type

    Fusionprotein

    背景

    Alternative Names: Interleukin-21,IL-21, Za11, IL21IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
    Alternative Names: Interleukin-21 (IL-21), also known as Za11, is a member of the IL-15/IL-21 family. IL-21 is expressed in activated CD4-positive T-cells, no expressed in CD8-positive T-cells, B-cells and monocytes.

    分子量

    15.6 kDa

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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