Myoglobin Protein (MB)
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北京 101111
Quick Overview for Myoglobin Protein (MB) (ABIN1880424)
抗原
See all Myoglobin (MB) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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Myoglobin (MB) (AA 2-100) protein (GST tag)
MB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Myoglobin (MB) (AA 2-154) protein (His tag)MB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Myoglobin (MB) (AA 2-154) protein (His-IF2DI Tag)MB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Myoglobin (MB) (AA 1-154) protein (His tag)MB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 50 mM Tris-HCl ( pH 8.0), 300 mM NaCl with 0.1 % SKL.
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储存条件
- 4 °C
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储存方法
- Ship at 4°C. Upon receipt, aliquot and store at 2-8°C for long term. Avoid repeated freeze and thaw cycles.
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- Myoglobin (MB)
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别名
- Myoglobin
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背景
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Synonyms: Myoglobin, MB, PVALB
Description: Recombinant full length human Myoglobin protein with molecular weight 17.8 kDa.
Background: Myoglobin, MB is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals. It is a cytoplasmic hemoprotein, expressed solely in cardiac myocytes and oxidative skeletal muscle fibers, that reversibly binds O2 by its heme residue, a porphyrin ring:iron ion complex. MB is a single-chain globular protein of 153 or 154 amino acids, containing a heme prosthetic group in the center around which the remaining apoprotein folds. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure. It is a sensitive marker for muscle injury, making it a potential marker for heart attack in patients with chest pain. However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB, cTnT, ECG, and clinical signs should be taken into account to make the diagnosis.
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分子量
- 17.8 kDa
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途径
- Brown Fat Cell Differentiation
抗原
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