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IFN alpha 2b 蛋白

This anti-IFN alpha 2b antibody (ABIN1880391) is a Escherichia coli (E. coli) antibody detecting IFN alpha 2b in . Suitable for Human.
产品编号 ABIN1880391
发货至: 中国

Quick Overview for IFN alpha 2b 蛋白 (ABIN1880391)

抗原

IFN alpha 2b

蛋白类型

Recombinant

宿主

资源

  • 2
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with sterile 18 mΩ/cm^3 H2O.

    缓冲液

    10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

    储存液

    Without preservative

    储存条件

    4 °C
  • 抗原

    IFN alpha 2b

    背景

    IFN-alpha, a multifunctional cytokine important in the innate immune system, has been proposed to play a major pathogenic role in the development of systemic lupus erythematosus in humans and mice. IFNA bound complement component receptor-2 (CR2) in the same affinity range as other CR2 ligands. Asokan et al. (2006) proposed that the roles of CR2 and IFNA in development of autoimmunity may be mechanistically linked to pathogenesis of systemic lupus erythematosus. Interferon-alpha and -beta (IFN-alpha/beta) and the tumour suppressor p53 are essential for the induction of apoptosis in cancerous cells and in antiviral immune responses, respectively. The transcription of the p53 gene is induced by IFN-alpha/beta, accompanied by an increase in p53 protein level. IFN-alpha/beta signalling itself does not activate p53, rather, it contributes to boosting p53 responses to stress signals.

    分子量

    19.2 +/- 1.9 kDa
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