FABP Heart 蛋白
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北京 101111
Quick Overview for FABP Heart 蛋白 (ABIN1880369)
抗原
蛋白类型
宿主
资源
纯度
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 20 mM Tris-HCL, 140 mM NaCl, 2 mM EDTA (pH 8.0)
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储存液
- Without preservative
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储存条件
- 4 °C
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- FABP Heart
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背景
- Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.
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分子量
- 15 kDa
抗原
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