Epididymis Protein 4 (HE-4) (Active) 蛋白
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北京 101111
Quick Overview for Epididymis Protein 4 (HE-4) (Active) 蛋白 (ABIN1880368)
抗原
蛋白类型
生物活性
宿主
资源
应用范围
纯度
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Tris-HCL ( pH 7.4±0.2) with 0.2 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- Epididymis Protein 4 (HE-4)
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别名
- Epididymis Protein 4
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背景
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Synonyms: Human epididymis protein 4, HE4, WAP four-disulfide core domain protein 2, WFDC2
Description: Recombinant full length human HE4 protein with molecular weight 14 kDa.
Background: WAP four-disulfide core domain protein 2,also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs(epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types ofEOCs.
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分子量
- 14 kDa
抗原
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