C-Peptide 蛋白
This Recombinant C-Peptide protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN1880359
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for C-Peptide 蛋白 (ABIN1880359)
抗原
See all C-Peptide 蛋白
C-Peptide
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 % by HPLC & SDS-PAGE
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10mM PBS (pH 7.5)
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储存液
- Without preservative
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储存条件
- 4 °C
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- C-Peptide
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背景
- Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.
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