C-Peptide 蛋白
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % by HPLC & SDS-PAGE
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- 抗原 See all C-Peptide 蛋白
- C-Peptide
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 纯度
- > 95 % by HPLC & SDS-PAGE
- Top Product
- Discover our top product C-Peptide 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10mM PBS (pH 7.5)
- 储存液
- Without preservative
- 储存条件
- 4 °C
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- 抗原
- C-Peptide
- Abstract
- C-Peptide 产品
- 背景
- Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.
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