C-Peptide 蛋白
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北京 101111
Quick Overview for C-Peptide 蛋白 (ABIN1880359)
抗原
See all C-Peptide 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM PBS( pH 7.5) without preservative.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- C-Peptide
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背景
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Synonyms: C-peptide, Connecting peptide
Description: Recombinant full length human C-Peptide protein.
Background: Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.
抗原
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