S100A1B (Active) 蛋白
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北京 101111
Quick Overview for S100A1B (Active) 蛋白 (ABIN1880350)
抗原
蛋白类型
生物活性
宿主
资源
应用范围
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM PBS( pH 7.4).
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- S100A1B
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背景
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Description: Purified human S100A1B protein.
Background: S100 proteins, such as S100A1 (S100 calcium-binding protein A1), are small, acidic Ca(2+)-binding proteins that transduce Ca(2+) signals via interaction with intracellular target proteins. The protein encoded by this gene is a member of the S100 family of proteins containing 4 EF-hand calcium-binding motifs in its dimerized form. S100A1 is preferentially expressed in myocardial tissue and has been found to colocalize with the sarcoplasmic reticulum (SR) and the contractile filaments in cardiac tissue. Its overexpression enhances cardiac contractile performance and establish the concept of S100A1 as a regulator of myocardial contractility. S100A1 thus improves cardiac contractile performance both by regulating SR Ca(2+) handling and myofibrillar Ca(2+) responsiveness.
抗原
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