Free PSA 蛋白
This Native Free PSA protein is expressed in Human.
产品编号 ABIN1880349
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Free PSA 蛋白 (ABIN1880349)
抗原
Free PSA (fPSA)
(Free Prostate Specific Antigen (fPSA))
蛋白类型
Native
宿主
人
资源
Human
纯度
> 90 % by SDS-PAGE
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纯化方法
- Purified
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M PBS (pH 7.4 +/- 0.2)
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储存液
- Without preservative
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储存条件
- 4 °C
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- Free PSA (fPSA) (Free Prostate Specific Antigen (fPSA))
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别名
- Free PSA
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背景
- Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific. PSA is a major protein in semen, where its function is to cleave semenogelins in the seminal coagulum. PSA is secreted into prostatic ducts as an inactive 244-amino acid proenzyme (proPSA) that is activated by cleavage of seven N-terminal amino acids. Measurement of free versus total PSA can increase specificity for PCa. PSA is also widely used to monitor responses to therapy and is under investigation as a therapeutic target.
抗原
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