Endoglin Protein (ENG) (AA 26-176) (His-TRX)
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Quick Overview for Endoglin Protein (ENG) (AA 26-176) (His-TRX) (ABIN1692461)
抗原
See all Endoglin (ENG) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 26-176
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标记
- This Endoglin protein is labelled with His-TRX.
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原理
- Recombinant Human Endoglin/CD105 (N-Trx, 6His)
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序列
- MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ETVHCDLQPV GPERDEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA Q
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产品特性
- Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx, 6His tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Endoglin (ENG) (AA 26-586) (Active) protein (His-Avi Tag)
ENG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Endoglin (ENG) (AA 1-658) protein (GST tag)ENG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endoglin (ENG) (AA 27-658) protein (GST tag)ENG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endoglin (ENG) (AA 394-581) protein (His-IF2DI Tag)ENG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Endoglin (ENG) (AA 27-581) (Active) protein (His tag)ENG 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Endoglin (ENG) (AA 26-586) protein (His tag)ENG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Supplied as a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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注意事项
- minimize freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- Endoglin (ENG)
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别名
- Endoglin
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Sub Type
- Fusionprotein
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背景
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Alternative Names: Endoglin, END, CD105, ENGEndoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
Alternative Names: Endoglin, END, CD105, ENG -
分子量
- 33.6 kDa
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UniProt
- P17813
抗原
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