UBE2K Protein (AA 1-200) (His tag,SUMO Tag)
Quick Overview for UBE2K Protein (AA 1-200) (His tag,SUMO Tag) (ABIN1692389)
抗原
See all UBE2K 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-200
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标记
- This UBE2K protein is labelled with His tag,SUMO Tag.
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原理
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-6His, SUMO tag)
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序列
- MGHHHHHHGS DSEVNQEAKP EVKPEVKPET HINLKVSDGS SEIFFKIKKT TPLRRLMEAF AKRQGKEMDS LRFLYDGIRI QADQAPEDLD MEDNDIIEAH REQIGGMANI AVQRIKREFK EVLKSEETSK NQIKVDLVDE NFTELRGEIA GPPDTPYEGG RYQLEIKIPE TYPFNPPKVR FITKIWHPNI SSVTGAICLD ILKDQWAAAM TLRTVLLSLQ ALLAAAEPDD PQDAVVANQY KQNPEMFKQT ARLWAHVYAG APVSSPEYTK KIENLCAMGF DRNAVIVALS SKSWDVETAT ELLLSN
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产品特性
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Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-6His, SUMO tag)
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (His tag)
UBE2K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (GST tag)UBE2K 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Transcript Variant 3) protein (His tag)UBE2K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2K 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- -80 °C
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储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
有效期
- 6 months
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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别名
- Ubiquitin-Conjugating Enzyme E2 K/UBE2K
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背景
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Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn200) of Human UBE2K fused with a 6His tag at the N-terminus.
Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins. -
分子量
- 34.5 kDa
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UniProt
- P61086
抗原
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