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IL10RB Protein (C-Term, Extracellular Domain)

This Recombinant IL10RB protein is expressed in HEK-293 Cells.
产品编号 ABIN1684696
发货至: 中国

Quick Overview for IL10RB Protein (C-Term, Extracellular Domain) (ABIN1684696)

抗原

See all IL10RB 蛋白
IL10RB (Interleukin 10 Receptor, beta (IL10RB))

蛋白类型

Recombinant

宿主

  • 12
  • 3
  • 3
小鼠

资源

  • 6
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HEK-293 Cells

纯度

> 90 %, as determined by SDS-PAGE and HPLC
  • 产品特性

    C-Term, Extracellular Domain

    序列

    MAPCVAGWLG GFLLVPALGM IPPPEKVRMN SVNFKNILQW EVPAFPKTNL TFTAQYESYR SFQDHCKRTA STQCDFSHLS KYGDYTVRVR AELADEHSEW VNVTFCPVED TIIGPPEMQI 130140150160170180ESLAESLHLR FSAPQIENEP ETWTLKNIYD SWAYRVQYWK NGTNEKFQVV SPYDSEVLRN 1900010203040LEPWTTYCIQ VQGFLLDQNR TGEWSEPICE RTGNDEITPS WIVAIILIVS VLVVFLFLLG 5060708090300CFVVLWLIYK KTKHTFRSGT SLPQHLKEFL GHPHHSTFLL FSFPPPEEAE VFDKLSIISE 310320330340ESEGSKQSPE DNCASEPPSD PGPRELESKD EAPSPPHDDP KLLTSTSEV

    特异性

    DNA sequence encoding extracellular domain of Mouse IL-10RB fused to a C-terminal polyHis tag was expressed in HEK cells.

    产品特性

    Recombinant Mouse Interleukin-10RB is a monomer consisting of12 amino acid residue subunits, and migrates as an approximately 46 kDa protein under reducing conditions in SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

    缓冲液

    PBS solution pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    有效期

    12-24 months
  • 抗原

    IL10RB (Interleukin 10 Receptor, beta (IL10RB))

    别名

    IL10RB

    背景

    TNF-beta TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells.

    UniProt

    Q61190
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