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EPOR Protein (C-Term, Extracellular Domain)

This Recombinant EPOR protein is expressed in HEK-293T Cells.
产品编号 ABIN1684690
发货至: 中国

Quick Overview for EPOR Protein (C-Term, Extracellular Domain) (ABIN1684690)

抗原

EPOR (Erythropoietin Receptor (EPOR))

蛋白类型

Recombinant

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小鼠

资源

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HEK-293T Cells

纯度

> 97 %, as determined by SDS-PAGE and HPLC
  • 产品特性

    C-Term, Extracellular Domain

    特异性

    Optimized DNA sequence encoding extracellular domain of mouse erythropoietin receptor including a C-terminal His tag was expressed in HEK293 cells.

    产品特性

    Recombinant mouse EPO receptor is a monomer protein consisting of37 amino acid residue subunits, due to glycosylation migrates as an approximately 35 kDa protein on SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • 限制

    仅限研究用
  • 缓冲液

    PBS solution, pH7.2

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    有效期

    12-24 months
  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    EPOR

    背景

    Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils monocytes and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis and the expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy

    UniProt

    P14753

    途径

    JAK/STAT Signaling
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