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CD48 Protein (CD48) (C-Term, Extracellular Domain)

This Recombinant CD48 protein is expressed in HEK-293T Cells.
产品编号 ABIN1684678
发货至: 中国

Quick Overview for CD48 Protein (CD48) (C-Term, Extracellular Domain) (ABIN1684678)

抗原

See all CD48 蛋白
CD48

蛋白类型

Recombinant

生物活性

Active

宿主

  • 18
  • 7
  • 3
小鼠

资源

  • 14
  • 4
  • 3
  • 2
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  • 1
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HEK-293T Cells

纯度

> 95 %, as determined by SDS-PAGE and HPLC
  • 产品特性

    C-Term, Extracellular Domain

    特异性

    Optimized DNA sequence encoding extracellular domain of Mouse CD48 including a C-terminal 6His tag was expressed in HEK293 cells.

    产品特性

    Recombinant Mouse CD48 is a monomer protein consisting of05 amino acid residue subunits, due to glycosylation migrates as an approximately 40 kDa protein on SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • 说明

    The activity was tested by immobilized recombinant mouse CD48 (10 µg/mL) ability to bind recombinant CD2 with a linear range of 0-100 ng/mL.

    限制

    仅限研究用
  • 缓冲液

    PBS solution, pH7.2

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    有效期

    12-24 months
  • 抗原

    CD48

    别名

    CD48

    背景

    IL6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T-cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT-1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T-cells, mitogen-activated B-cells, peripheral monocytes and some macrophage- and B-cell derived tumor cell types. It is not expressed in resting B-cells but in resting T-cells. The IL6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.

    UniProt

    P18181
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