CD48 Protein (CD48) (C-Term, Extracellular Domain)
Quick Overview for CD48 Protein (CD48) (C-Term, Extracellular Domain) (ABIN1684678)
抗原
See all CD48 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- C-Term, Extracellular Domain
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特异性
- Optimized DNA sequence encoding extracellular domain of Mouse CD48 including a C-terminal 6His tag was expressed in HEK293 cells.
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产品特性
- Recombinant Mouse CD48 is a monomer protein consisting of05 amino acid residue subunits, due to glycosylation migrates as an approximately 40 kDa protein on SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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说明
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The activity was tested by immobilized recombinant mouse CD48 (10 µg/mL) ability to bind recombinant CD2 with a linear range of 0-100 ng/mL.
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限制
- 仅限研究用
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缓冲液
- PBS solution, pH7.2
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
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有效期
- 12-24 months
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- CD48
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别名
- CD48
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背景
- IL6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T-cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT-1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T-cells, mitogen-activated B-cells, peripheral monocytes and some macrophage- and B-cell derived tumor cell types. It is not expressed in resting B-cells but in resting T-cells. The IL6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.
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UniProt
- P18181
抗原
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