CD200 Protein (CD200) (C-Term, Extracellular Domain)
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Quick Overview for CD200 Protein (CD200) (C-Term, Extracellular Domain) (ABIN1684663)
抗原
See all CD200 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- C-Term, Extracellular Domain
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特异性
- Optimized DNA sequence encoding extracellular domain of Mouse CD200 including a C-terminal 6His tag was expressed in HEK293 cells.
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产品特性
- Recombinant Mouse CD200 is a monomer protein consisting of13 amino acid residue subunits, due to glycosylation migrates as an approximately 40-45kDa protein on SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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CD200 (CD200) (AA 31-232) protein (His tag)
CD200 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 (CD200) (AA 56-257) protein (His tag)CD200 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 (CD200) (AA 31-232) protein (His tag)CD200 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD200 (CD200) (AA 34-124) protein (GST tag)CD200 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD200 (CD200) (AA 31-232) protein (hIgG-His-tag)CD200 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS
CD200 (CD200) (Active) protein (His tag)CD200 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD200 (CD200) (AA 31-232) protein (Fc Tag)CD200 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD200 (CD200) (AA 31-232) protein (Fc Tag,AVI tag,Biotin)CD200 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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说明
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The activity was tested by the ability of immobilized recombinant mouse CD200 (1 µg/mL,100 µL/well) to bind mouse CD200R1 with a linear range of 1-200 ng/mL
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限制
- 仅限研究用
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缓冲液
- PBS solution, pH7.2
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- The lyophilized antibody is stable for at least 1 year from date of receipt at -20 °C. Upon reconstitution, this antibody can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months without detectable loss of activity.
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有效期
- 12 months
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- CD200
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别名
- CD200
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背景
- CD7 is a 40-kD member of the Ig gene superfamily that is expressed on a major subset of human peripheral T lymphocytes and NK cells. CD7 can complex with CD3 and CD45 molecules, and CD7 signaling involves both protein kinase C and protein tyrosine kinase. CD7 has been shown to be a functional signal-transducing molecule on resting NK cells. Although the function of CD7 is unknown, studies suggest that CD7 may be involved in T and NK cell activation and/or adhesion. In TCRbeta T cells, cross-linking of CD7 leads to rapid increases in intracellular calcium concentrations, induces CD7 cytoplasmic domain association with phosphotidylinositol-3-kinase, synergizes with submitogenic amounts of CD3 mAbs to induce T cell activation, modulates T cell adhesion, and increases T cell IL-2 production and IL-2 receptor expression. In TCR T cells, cross-linking of CD7 leads to cell activation and induction of TNF-a, TNF-b, and granulocyte-macrophage CSF mRNA.
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UniProt
- O54901
抗原
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