PDGF-AA Homodimer (Homodimer) (Active) 蛋白
This Recombinant PDGF-AA Homodimer protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN1589624
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for PDGF-AA Homodimer (Homodimer) (Active) 蛋白 (ABIN1589624)
抗原
PDGF-AA Homodimer
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 % by SDS-PAGE
-
-
产品特性
- Homodimer
-
原理
- PDGF-AA
-
序列
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
-
特异性
- Chromosomal location:7p22
-
产品特性
- Length (aa):125
-
内毒素水平
- < 0.1 ng per ug of PDGF-AA
-
-
PDGF-AA Homodimer protein
宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
PDGF-AA Homodimer protein宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
-
-
应用备注
- The biological activity was determined by the induction of proliferation in NHDF cells (Normal Human Dermal Fibroblasts).
-
说明
-
Cytokines & Growth Factors
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Centrifuge vial prior to opening. The lyophilized PDGF-AA should be reconstituted in water to a concentration not lower than 50 μg/mL. For long term storage we recommend to add at least 0.1 % human or bovine serum albumin.
-
缓冲液
- 50 mM acetic acid
-
注意事项
- Centrifuge vial prior to opening. Avoid repeated freeze-thaw cycles.
-
储存条件
- RT,-20 °C,-80 °C
-
储存方法
- The lyophilized PDGF-AA is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted PDGF-AA is best stored at -20°C to -70°C. Avoid repeated freeze-thaw cycles.
-
-
- PDGF-AA Homodimer
-
别名
- PDGF-AA
-
背景
-
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).
Synonyms: PDGFA, PDGF1, PDGF-A -
分子量
- 28.5 kDa
-
基因ID
- 5154
-
NCBI登录号
- NM_002607, NP_002598
-
UniProt
- P04085
抗原
-
You are here:
