PLGF Protein (Homodimer)
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北京 101111
Quick Overview for PLGF Protein (Homodimer) (ABIN1589562)
抗原
See all PLGF (PGF) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- Homodimer
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原理
- PlGF
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序列
- ALSAGNNSTE VEVVPFNEVW GRSYCRPMEK LVYILDEYPD EVSHIFSPSC VLLSRCSGCC GDEGLHCVPI KTANITMQIL KIPPNRDPHF YVEMTFSQDV LCECRPILET TKAERRKTKG KRKRSRNSQT EEPHP
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特异性
- Chromosomal location:12 D, 12 39.0 cM
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产品特性
- Length (aa):135/132
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Placenta Growth Factor (PGF) (AA 19-221) protein (Fc Tag)
PGF 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Placenta Growth Factor (PGF) (Active) proteinPGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Placenta Growth Factor (PGF) (AA 19-158) protein (Fc Tag)PGF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Placenta Growth Factor (PGF) (AA 19-170) protein (Fc Tag)PGF 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Placenta Growth Factor (PGF) (AA 19-170) (Active) protein (His tag)PGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Placenta Growth Factor (PGF) (AA 19-221) (Active) protein (Fc Tag)PGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Placenta Growth Factor (PGF) (AA 19-149) protein (His-IF2DI Tag)PGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Placenta Growth Factor (PGF) (AA 24-158) protein (His-IF2DI Tag)PGF 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Placenta Growth Factor (PGF) protein (His tag)PGF 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Placenta Growth Factor (PGF) (Active) protein (His tag)PGF 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
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应用备注
- Measured by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. Recombinant mouse PlGF can bind to immobilized rh-sFlt-1 (100 ng/well) with a linear range at 0.5 - 10 ng/mL.
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说明
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Cytokines & Growth Factors
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. The lyophilised PlGF is supplied in lyophilized form with carrier-protein (BSA) and can be reconstituted with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
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缓冲液
- 25 mM Tris, 75 mM NaCl pH 8.5
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储存条件
- RT,-20 °C,-80 °C
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储存方法
- The lyophilized mouse PIGF, though stable at room temperature, is best stored in working aliquots at -20°C to -70°C.
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- PLGF (PGF) (Placenta Growth Factor (PGF))
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别名
- PlGF
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背景
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Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF-1, PlGF-2 and PlGF-3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 65 % amino acid identity with human PlGF-2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.
Synonyms: Pgf, PlGF, Plgf, AI854365, placental growth factor -
分子量
- ~40 kDa
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基因ID
- 18654
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NCBI登录号
- NM_008827, NP_032853
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UniProt
- P49764
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途径
- VEGFR1 Specific Signals
抗原
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