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PLGF Protein (Homodimer)

This Recombinant PLGF protein is expressed in Insect Cells.
产品编号 ABIN1589562
发货至: 中国

Quick Overview for PLGF Protein (Homodimer) (ABIN1589562)

抗原

See all PLGF (PGF) 蛋白
PLGF (PGF) (Placenta Growth Factor (PGF))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 20
  • 7
  • 4
  • 3
  • 1
小鼠

资源

  • 14
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Insect Cells

纯度

> 95 % by SDS-PAGE
  • 产品特性

    Homodimer

    原理

    PlGF

    序列

    ALSAGNNSTE VEVVPFNEVW GRSYCRPMEK LVYILDEYPD EVSHIFSPSC VLLSRCSGCC GDEGLHCVPI KTANITMQIL KIPPNRDPHF YVEMTFSQDV LCECRPILET TKAERRKTKG KRKRSRNSQT EEPHP

    特异性

    Chromosomal location:12 D, 12 39.0 cM

    产品特性

    Length (aa):135/132
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  • 应用备注

    Measured by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. Recombinant mouse PlGF can bind to immobilized rh-sFlt-1 (100 ng/well) with a linear range at 0.5 - 10 ng/mL.

    说明

    Cytokines & Growth Factors

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. The lyophilised PlGF is supplied in lyophilized form with carrier-protein (BSA) and can be reconstituted with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.

    缓冲液

    25 mM Tris, 75 mM NaCl pH 8.5

    储存条件

    RT,-20 °C,-80 °C

    储存方法

    The lyophilized mouse PIGF, though stable at room temperature, is best stored in working aliquots at -20°C to -70°C.
  • 抗原

    PLGF (PGF) (Placenta Growth Factor (PGF))

    别名

    PlGF

    背景

    Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF-1, PlGF-2 and PlGF-3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 65 % amino acid identity with human PlGF-2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.
    Synonyms: Pgf, PlGF, Plgf, AI854365, placental growth factor

    分子量

    ~40 kDa

    基因ID

    18654

    NCBI登录号

    NM_008827, NP_032853

    UniProt

    P49764

    途径

    VEGFR1 Specific Signals
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