IL-37 Protein (His tag)
Quick Overview for IL-37 Protein (His tag) (ABIN1344168)
抗原
See all IL-37 (IL37) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This IL-37 protein is labelled with His tag.
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原理
- IL-37 (aa 46-218) (human) (rec.) (His)
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交叉反应
- 人
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产品特性
- Human IL-37 (aa Val46-Asp218) is fused at the C-terminus to a His-tag.
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过滤
- Sterile filtered
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内毒素水平
- <0.1EU/μg purified protein (LAL test).
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Interleukin 37 (IL37) (AA 1-218) protein (GST tag)
IL37 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 37 (IL37) (Active) proteinIL37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in distilled water.
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浓度
- Lot specific
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缓冲液
- Lyophilized from 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
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注意事项
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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有效期
- 6 months
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- IL-37 (IL37) (Interleukin 37 (IL37))
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别名
- IL-37
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背景
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Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1
IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
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分子量
- ~20kDa (SDS-PAGE)
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UniProt
- Q9NZH6
抗原
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