Calreticulin Protein (CALR) (His tag)
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Quick Overview for Calreticulin Protein (CALR) (His tag) (ABIN1344123)
抗原
See all Calreticulin (CALR) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Calreticulin protein is labelled with His tag.
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原理
- Calreticulin (human) (rec.) (His)
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交叉反应
- 人
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产品特性
- Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag.
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过滤
- Sterile filtered
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内毒素水平
- <1EU/μg purified protein (LAL test).
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Calreticulin (CALR) (AA 25-199) protein (His-IF2DI Tag)
CALR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Calreticulin (CALR) (AA 1-417) protein (GST tag)CALR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calreticulin (CALR) (AA 18-417) protein (His tag)CALR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Calreticulin (CALR) (AA 18-417) protein (His tag)CALR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
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注意事项
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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有效期
- 6 months
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- Calreticulin (CALR)
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别名
- Calreticulin
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背景
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CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
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分子量
- ~55kDa (SDS-PAGE)
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UniProt
- P27797
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途径
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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