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Calreticulin Protein (CALR) (His tag)

This Recombinant Calreticulin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1344123
发货至: 中国

Quick Overview for Calreticulin Protein (CALR) (His tag) (ABIN1344123)

抗原

See all Calreticulin (CALR) 蛋白
Calreticulin (CALR)

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

>90 % (SDS-PAGE)
  • 标记

    This Calreticulin protein is labelled with His tag.

    原理

    Calreticulin (human) (rec.) (His)

    交叉反应

    产品特性

    Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag.

    过滤

    Sterile filtered

    内毒素水平

    <1EU/μg purified protein (LAL test).
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.

    注意事项

    After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

    有效期

    6 months
  • 抗原

    Calreticulin (CALR)

    别名

    Calreticulin

    背景

    CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60

    Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.

    分子量

    ~55kDa (SDS-PAGE)

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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