HFE Protein (His tag)
Quick Overview for HFE Protein (His tag) (ABIN1098722)
抗原
See all HFE 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This HFE protein is labelled with His tag.
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Hemochromatosis (HFE) (AA 115-205) protein (GST tag)
HFE 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AP, AA, WB
Hemochromatosis (HFE) proteinHFE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % pure SDS
Hemochromatosis (HFE) (Transcript Variant 6) protein (Myc-DYKDDDDK Tag)HFE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 9) protein (Myc-DYKDDDDK Tag)HFE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HFE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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说明
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Synonyms: Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml (determined by Bradford assay)
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缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
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储存条件
- 4 °C
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储存方法
- Avoid repeated freezing and thawing cycles.
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- HFE (Hemochromatosis (HFE))
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别名
- HFE
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背景
- HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E.coli.
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分子量
- 35.7kDa (308aa)
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NCBI登录号
- NP_000401
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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