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LTA Protein (AA 35-205)

This Recombinant LTA protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1097674
发货至: 中国

Quick Overview for LTA Protein (AA 35-205) (ABIN1097674)

抗原

See all LTA 蛋白
LTA (Lymphotoxin-alpha (LTA))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 35-205

    原理

    Recombinant Human Tumor Necrosis Factor β/TNFβ

    序列

    MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL

    产品特性

    Recombinant Human Tumor Necrosis Factor beta/TNF-beta is produced by our E. coli expression system. The target protein is expressed with sequence (Leu35-Leu205) of Human TNF-beta.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    LTA (Lymphotoxin-alpha (LTA))

    别名

    tnf-beta

    物质类

    Chemical

    背景

    Tumor Necrosis Factor beta (TNF-beta) is a secreted protein belonging to the tumor necrosis factor family. TNF-beta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-beta forms heterotrimers with lymphotoxin-beta, which anchors TNF-beta to the cell surface. TNF-beta mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-beta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
    Alternative Names: Lymphotoxin-Alpha, LT-Alpha, TNF-Beta, Tumor Necrosis Factor Ligand Superfamily Member 1, LTA, TNFB, TNFSF1

    分子量

    18.8 kDa

    UniProt

    P01374

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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