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CXCL12 Protein (AA 22-89)

This Recombinant CXCL12 protein is expressed in Escherichia coli (E. coli).
产品编号 ABIN1097490
发货至: 中国

Quick Overview for CXCL12 Protein (AA 22-89) (ABIN1097490)

抗原

See all CXCL12 蛋白
CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 22-89

    原理

    Recombinant Human C-X-C Motif Chemokine 12/CXCL12/SDF-1 (22-89)

    序列

    KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK

    产品特性

    Recombinant Human C-X-C Motif Chemokine 12/CXCL12 (22-89) is produced with our E. coli expression system. The target protein is expressed with sequence (Lys22-Lys89) of Human CXCL12.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

    别名

    sdf-1-alpha

    背景

    Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1alpha and SDF1beta are identical except for the four residues present in the C-terminus of SDF1beta but absent from SDF1alpha. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.
    Alternative Names: Stromal Cell-Derived Factor 1, SDF-1, hSDF-1, C-X-C Motif Chemokine 12, Intercrine Reduced in Hepatomas, IRH, hIRH, Pre-B Cell Growth-Stimulating Factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B

    分子量

    8.12 kDa

    UniProt

    P48061

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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