PDGF-BB Homodimer (AA 82-190) 蛋白
Quick Overview for PDGF-BB Homodimer (AA 82-190) 蛋白 (ABIN1097308)
抗原
蛋白类型
宿主
资源
纯度
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产品特性
- AA 82-190
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原理
- Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB
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序列
- MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
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产品特性
- Recombinant Human Platelet-Derived Growth Factor Subunit B/PDGFB is produced by our E. coli expression system. The target protein is expressed with sequence (Ser82-Thr190) of Human PDGFB.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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PDGF-BB Homodimer (Active) protein (His tag)
宿主: 人 宿主: 酵母菌 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
PDGF-BB Homodimer protein宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 98 % as determined by reducing SDS-PAGE.
PDGF-BB Homodimer (AA 82-190) (Active) protein宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing (R) and non-reducing (NR) SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- PDGF-BB Homodimer
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别名
- pdgf-bb
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背景
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Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Alternative Names: Platelet-Derived Growth Factor Subunit B, PDGF Subunit B, PDGF-2, Platelet-Derived Growth Factor B Chain, Platelet-Derived Growth Factor Beta Polypeptide, Proto-Oncogene c-Sis, Becaplermin, PDGFB, PDGF2, SIS -
分子量
- 12.42 kDa
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UniProt
- P01127
抗原
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