IL-37 Protein (AA 53-218)
This Recombinant IL-37 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for IL-37 Protein (AA 53-218) (ABIN1096915)
抗原
See all IL-37 (IL37) 蛋白
IL-37 (IL37)
(Interleukin 37 (IL37))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 53-218
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原理
- Recombinant Human Interleukin-37/IL-37
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序列
- MKNLNPKKFS IHDQDHKVLV LDSGNLIAVP DKNYIRPEIF FALASSLSSA SAEKGSPILL GVSKGEFCLY CDKDKGQSHP SLQLKKEKLM KLAAQKESAR RPFIFYRAQV GSWNMLESAA HPGWFICTSC NCNEPVGVTD KFENRKHIEF SFQPVCKAEM SPSEVSD
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产品特性
- Recombinant Human Interleukin-37/IL-37 is produced with our E. coli expression system. The target protein is expressed with sequence (Lys27-Asp192) of Human IL-37.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Interleukin 37 (IL37) (AA 1-218) protein (GST tag)
IL37 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 37 (IL37) (Active) proteinIL37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM DTT, pH 7.4.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- IL-37 (IL37) (Interleukin 37 (IL37))
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别名
- Interleukin-37/IL-37
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背景
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Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 Ralpha with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.
Alternative Names: Interleukin-37, FIL1 Zeta, IL-1X, Interleukin-1 Family Member 7, IL-1F7, Interleukin-1 Homolog 4, IL-1H, IL-1H4, Interleukin-1 Zeta, IL-1 Zeta, Interleukin-1-Related Protein, IL-1RP1, Interleukin-23, IL-37, IL37, FIL1Z, IL1F7, IL1H4, IL1RP1 -
分子量
- 18.7 kDa
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UniProt
- Q9NZH6
抗原
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