IL17F Protein (Homodimer)
Quick Overview for IL17F Protein (Homodimer) (ABIN1096909)
抗原
See all IL17F 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- Homodimer
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原理
- Recombinant Human Interleukin-17F/IL-17F
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序列
- MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
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产品特性
- Recombinant Human Interleukin-17F/IL-17F produced in E. coli is a disulfide-linked homodimer of 30.1 kDa, consisting of two non-glycosylated polypeptide chains with 134 amino acids each.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Interleukin 17F (IL17F) (AA 31-163) protein (His-Avi Tag,Biotin)
IL17F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17F (IL17F) (AA 29-161) protein (His-Avi Tag)IL17F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17F (IL17F) (AA 31-163) protein (His tag)IL17F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17F (IL17F) (AA 29-161) protein (His-Avi Tag,Biotin)IL17F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17F (IL17F) (AA 31-163) protein (His tag)IL17F 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17F (IL17F) (AA 31-163) (Active) protein (His tag)IL17F 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17F (IL17F) (AA 31-163) (Active) protein (His tag)IL17F 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17F (IL17F) protein (His tag)IL17F 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 17F (IL17F) (AA 28-161) protein (His tag)IL17F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 17F (IL17F) (Active) protein (His tag)IL17F 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
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说明
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Biological activity: ED50 is approximately 10 ng/ml as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells.Specific Activity of 1.0 x 105 IU/mg
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in 500 mM Acetic Acid.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- IL17F (Interleukin 17F (IL17F))
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别名
- il-17f
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背景
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Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
Alternative Names: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24, IL17F, IL24 -
分子量
- 30.1 kDa
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UniProt
- Q96PD4
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
抗原
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